Atkinson will line up at inside centre for George Skivington’s side who show two changes to their starting XV, with Jason Woodward back at full-back and Lloyd Evans returning at fly-half.

Meanwhile, Dean Richards has made three changes to his Newcastle side, as Philip van der Welt comes into the second row, Peter Lucock starts at inside centre and Nathan Earle replaces Adam Radwan on the right wing.

Elsewhere in the Gallagher Premiership, London Irish head to Exeter Chiefs with openside flanker Tom Pearson set to make his first appearance for Declan Kidney’s men.

Matt Rogerson captains the side from blindside flanker, while Will Goodrick-Clarke, Agustin Creevy and Ollie Hoskins are named in the front row. Nick Phipps and Paddy Jackson are the half-backs.

Zebre Parma show six changes for their United Rugby Championship clash against fellow Challenge Cup team Edinburgh Rugby at Stadio Lanfranchi.

Leonard Krumov comes into the second row alongside David Sisi, with tighthead prop Eduardo Bello added to the front row. Luca Andreani and Jimmy Tuivaiti are the starting flankers, while Erich Cronjé lines up on the left wing and Enrico Lucchin is at inside centre.

For Edinburgh, Scottish international Blair Kinghorn is among seven changes, which also include Cammy Hutchison and James Johnstone as the centres, with Jack Bain on the wing.

In the forwards, Jamie Hodgson and Pierce Phillips have been named as the second-row pairing, while Jamie Ritchie returns to captain the side at openside flanker.

Also in the United Rugby Championship on Saturday, Dragons face Heineken Champions Cup opposition in Cardiff Blues at Cardiff Arms Park.

In the TOP 14, bottom side Biarritz host Challenge Cup rivals CA Brive and Section Paloise travel to ASM Clermont Auvergne, while USAP visit Bordeaux and Lyon are also on the road, to Stade Français Paris.

Mark Atkinson will make his 150th appearance for Gloucester Rugby on Saturday as the Cherry and Whites host EPCR Challenge Cup rivals Newcastle Falcons in the Gallagher Premiership.