Exeter have the chance to win back-to-back domestic titles after seeing off Sale Sharks 40-30 in an enthralling clash at Sandy Park last weekend, with Jack Nowell bagging a brace and Joe Simmonds slotting over 15 points from the kicking tee.

Harlequins secured their final berth after overcoming 2020 Challenge Cup winners Bristol Bears in the most dramatic fashion, coming back from 28-5 down to eventually run out 43-36 victors after extra time at Ashton Gate.

British and Irish Lions trio Luke Cowan-Dickie, Jonny Hill and Sam Simmonds all start, whilst Stuart Hogg - also a part of the Lions contingent - is expected to feature off the replacements bench for Rob Baxter’s side.

Nowell marked his return to action last weekend by scoring two tries in the win over Sale and becomes the only Chiefs player to have featured in all six of Exeter’s Premiership finals.

For Harlequins, Billy Millard has made three changes from the side that defeated Bristol last week, including Springbok centre Andre Esterhuizen who plays for the first time since March having returned from suspension.

Back row James Chisholm also returns to the starting XV, having impressed with a try-scoring appearance from the bench last weekend whilst wing Cadan Murley starts following injury to outside back Aaron Morris in Bristol.

2020 Heineken Champions Cup winners Exeter Chiefs will be bidding for a second consecutive Gallagher Premiership title on Saturday when they take on Harlequins in the domestic decider at Twickenham Stadium.