Round 3 of this season’s European Rugby Challenge Cup gets underway on Friday night with a mouthwatering clash as 2018 semi-finalists Pau host Pool 2 leaders Worcester Warriors, who will be bidding to make it three Challenge Cup wins from as many matches. Worcester dominated European heavyweights Stade Français Paris 38-27 in the opening round before grinding out a 27-21 win over Ospreys at Sixways Stadium, while Pau crashed 27-0 at Ospreys before also defeating Stade, 21-15. Their game gets underway at 19:45 GMT on Friday, while the other Pool 2 fixture sees Ospreys entertain Stade at the Liberty Stadium on Saturday at 15:00 GMT. The other Friday match is an all-French affair, with both Grenoble and Agen desperate for a bonus-point win to boost their chances of escaping a tight Pool 5. The action is live on beIN SPORTS from Stade des Alpes at 19:45 GMT. Just points difference splits Pool 5 leaders Harlequins and second-placed Benetton Rugby before their meeting in Treviso on Saturday. Both sides comfortably won their opening home matches, but then fell to losses by single-figure margins. The action from Stadio Comunale di Monigo will be live on DAZN from 14:00 GMT. [jwplayer Hb2hpIx3] Pool 1 features two-time Challenge Cup winners ASM Clermont Auvergne, who have made the perfect start in their quest for a third success in the competition. They brushed Northampton Saints on the road in Round 1 before comfortably beating Saturday’s opponents, Timisoara Saracens, 70-12. Action from the Dan Paltinisanu Stadium gets underway at 12:30 GMT, while Northampton host Dragons in the other Pool 1 match at 15:00 GMT. 2018 Champions Cup quarter-finalists La Rochelle have also enjoyed a flawless start, swatting aside Enisei-STM with bonus-point victories in Krasnoyarsk and La Rochelle. They travel to resurgent Bristol Bears on Saturday, with the English club having traded wins with Zebre Rugby Club in their first two matches in Europe since promotion from England’s second tier. [jwplayer NYdva0dV] The Pool 4 meeting from Ashton Gate gets underway at 15:00 GMT, while Enisei-STM's home tie with Zebre is a 12:00 GMT start in Sochi. Round 3 ends with an intriguing Pool 3 meeting between Bordeaux-Bègles and Sale Sharks, who have lit up the competition with the return of European try machine Chris Ashton. The 31-year-old scored a hat-trick in Round 2 as Sale beat Connacht Rugby 34-13, leaving the English side top of Pool 3 with a maximum total of 10 points. That game at Stade Chaban-Delmas will be televised live on FRTV from 18:00 GMT, while Connacht host Perpignan at 15:00 GMT in Galway in the other Pool 3 game.