Mason Grady, who plays for 2018 EPCR Challenge Cup champions Cardiff Rugby, has been handed his Wales debut for their upcoming Six Nations match against England at the Principality Stadium on Saturday.

The 20-year-old centre Grady, who featured in all four of Cardiff’s EPCR Challenge Cup Pool A fixtures this season as they finished third to qualify for the Round of 16, is one of nine changes Warren Gatland has made to the Welsh starting side from the team that lost 35-7 to Scotland in Edinburgh.

Also among the changes is Leigh Halfpenny of Pool B winners Scarlets, who returns from injury at full-back.

The side will be captained by Halfpenny’s Scarlets teammate Ken Owens who starts as hooker, just as he did last time out. Cardiff’s Taulupe Faleta comes in at Number 8, while his fellow Cardiff player Josh Adams retains his place as wing.

Elsewhere, Ireland will take on Italy in Rome as they look to continue their perfect start to this year’s Six Nations.

EPCR Challenge Cup players will be in action for the Irish, with a trio of Connacht Rugby players all starting; Bundee Aki returns to the side at centre, while prop Finlay Bealham and wing Mack Hansen keep their places from the win in Dublin over France two weeks ago.