Henry Slade and Jack Willis, who play for Heineken Champions Cup clubs Exeter Chiefs and Stade Toulousain respectively, are two of the three changes made by England ahead of their second match of the Six Nations on Sunday against Italy.

England Head Coach Steve Borthwick named the Round of 16 qualifiers as two of his three personnel changes from the starting XV which lost to Scotland last weekend, with Bath Rugby’s centre Ollie Lawrence the third alteration.

A 2020 Heineken Champions Cup winner with Exeter Chiefs, Slade returns from injury to start at outside centre, with Captain and 2017 EPCR Player of the Year Owen Farrell moving to fly-half.

Meanwhile Willis, who will face Vodacom Bulls with Toulouse in the Heineken Champions Cup Round of 16, is the only change to the pack as he comes in at openside flanker.

The rest of the XV remains unchanged, while amongst the replacements Harlequins hooker Jack Walker will have the chance to make his debut for the national side.

For the Italians, Saracens’ Marco Riccioni steps in at prop to face a number of his club teammates.