Anthony Watson, who scored his maiden Heineken Champions Cup try for Leicester Tigers last December, starts on the wing for England as they take on Wales in the Six Nations in Cardiff on Saturday.

The 28-year-old joined Leicester from Bath Rugby last summer and scored a superb try in his first Heineken Champions Cup game for the club, helping them to a 23-17 win at Ospreys in Round 1.

Leicester, who went on to secure a home Round of 16 clash with Edinburgh Rugby on March 31, now boast four players in the England starting XV as Watson comes in as the only change following their victory over Italy a fortnight ago.

Full-back Freddie Steward retains his place in the back three, with scrum-half Jack van Poortvliet and lock Ollie Chessum also continuing.

There is further Heineken Champions Cup talent across the side again as Saracens’ Owen Farrell lines up at fly-half and his joined by three clubmates in hooker Jamie George, lock Maro Itoje and wing Maro Itoje.

Exeter Chiefs’ Henry Slade is at outside centre while Harlequins’ Alex Dombrandt is at No.8 and Stade Toulousain’s Jack Willis is at openside flanker.