Boffelli, who played in all three of Argentina’s Autumn Nations Series games, starts at full-back in a back three with fellow Argentine Ramiro Moyano and Damien Hoyland for Mike Blair’s men.

Hooker McBurney forms an Edinburgh front-row alongside returning Scottish international WP Nel at tighthead prop and South African loosehead prop Boan Venter.

Blindside flanker Nick Haining and No.8 Magnus Bradbury return from Autumn Nations Series duty with Scotland to start in a back-row with Luke Crosbie.

Hosts Dragons have called on tighthead prop Chris Coleman for his first start of the season in a front-row with hooker Taylor Davies and loosehead prop Greg Bateman.

Wales international Ben Carter is named in the second row with Joe Maksymiw, whereas captain Harri Keddie starts at blindside flanker in the Dragons back-row.

Jamie Roberts returns from injury to form a centre partnership with Jack Dixon, whereas director of rugby Dean Ryan sticks with a back three of full-back Jordan Williams, Jonah Holmes and Rio Dyer.

Elsewhere, 2020/21 Challenge Cup quarter finalists Benetton Rugby welcome Glasgow Warriors to the Stade Comunale di Monigo.

Luca Morisi, Edoardo Padovani, Michele Lamaro and Federico Ruzza, who all played in Italy’s 17-10 Autumn Nations Series win over Uruguay last weekend, feature in the Benetton starting XV.

Padovani starts on the left wing for Marco Bortolami’s side in a back three with full-back Rhyno Smith and Ratuya Tavuyara.

Inside centre Morisi is in midfield with Tommaso Menoncello, while Dewaldt Duvenage captains the side at scrum-half in a half-back partnership with Leonardo Marin.

Lamaro is in at openside flanker in a back-row with blindside flanker Giovanni Pettinelli and No.8 Toa Halafihi.

Lock Ruzza partners Carl Wegner in the second-row, whereas loosehead prop Federico Zani, hooker Gianmarco Lucchesi and tighthead prop Tiziano Pasquali form the front-row.

Meanwhile, in the TOP 14, EPCR Challenge Cup hopefuls RC Toulon and Lyon face each other at Stade Félix Mayol as Biarritz Olympique host Stade Français Paris. Section Paloise visit Stade Rochelais and CA Brive head to Stade Toulousain.

Edinburgh Rugby have handed debuts to Emiliano Boffelli and Adam McBurney in their United Rugby Championship clash against fellow EPCR Challenge Cup side Dragons at Rodney Parade on Saturday.