The English outfit realistically have little chance of making the quarter-finals but they will be keeping an eye on Leinster's result against Clermont in Dublin because the Irish province are only four points ahead of them in the Pool.
The Chiefs will want to finish has high up the Pool as they can and they have proved their European credentials, especially at home at Sandy Park and they will really fancy their chances against the Scarlets.
The Welsh region came into this tournament with a far amount of hype after Wales' Grand Slam success and exploits in the 2011 World Cup, but they have yet to record a win in this season's tournament.
The Scarlets have managed two losing bonus points but their heavy defeat to Clermont in France appears to have taken a heavy toll on them and they have nothing to play for but pride in Exeter.
• Scarlets' average of 232 metres gained per game is the lowest in the tournament.
• Scarlets have lost all three of their group games so far this season. They have never lost four on the trot.
• Luke Arscott is the joint-fourth top metre-maker in the tournament this season, having gained 264 metres so far.
• Exeter claimed their first ever Heineken Cup victory by winning the reverse fixture last weekend